SCHEMBL24155380

SCHEMBL24155380

CNCCCCC(NC(=O)[C@H](CCCCNC)NC)C(C)=O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KISS1R Q969F8 1/20 0.45
SIRT5 Q9NXA8 2/20 0.39
SIRT6 Q8N6T7 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
FOLH1 Q04609 1/20 0.35
GNPAT O15228 2/20 0.34
OPRK1 P41145 2/20 0.33
CPB2 Q96IY4 1/20 0.33
NMT2 O60551 1/20 0.32
NMT1 P30419 1/20 0.32
TLR2 O60603 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24155383 1.00 KISS1R (0.45) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL16221913 1.00 KISS1R (0.45) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL24155382 1.00 KISS1R (0.45) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL19035531 0.94 SIRT6 (0.45) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL18291772 0.94 SIRT6 (0.45) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL23054352 0.93 KISS1R (0.49) KISS1RSIRT5SIRT6SIRT1GNPAT
SCHEMBL21626605 0.93 KISS1R (0.49) KISS1RSIRT5SIRT6SIRT1GNPAT
SCHEMBL24155387 0.92 KISS1R (0.40) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL16221564 0.91 KISS1R (0.39) KISS1RSIRT5SIRT6SIRT1FOLH1
SCHEMBL23617774 0.89 MEN1 (0.46) KISS1RSIRT5SIRT6SIRT1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021260197-A1 ENHANCED OLIGONUCLEOTIDES FOR MODULATING FUBP1 EXPRESSION F. HOFFMANN-LA ROCHE AG (CH) 2021-12-30 WO disclosed