Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20834797 | 0.93 | TMPRSS2 (0.40) | TMPRSS2 | |
| SCHEMBL22372336 | 0.93 | TMPRSS2 (0.40) | TMPRSS2 | |
| SCHEMBL23054728 | 0.84 | — | — | |
| SCHEMBL22393486 | 0.84 | TMPRSS2 (0.40) | TMPRSS2 | |
| SCHEMBL23054725 | 0.84 | TMPRSS2 (0.30) | TMPRSS2 | |
| SCHEMBL20834799 | 0.83 | TMPRSS2 (0.39) | TMPRSS2 | |
| SCHEMBL22393459 | 0.83 | TMPRSS2 (0.39) | TMPRSS2 | |
| SCHEMBL20834794 | 0.82 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL20819183 | 0.82 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL25821374 | 0.81 | TMPRSS2 (0.38) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210060051-A1 | COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS | EMORY UNIVERSITY | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210060051-A1 | COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS | NOX1, NOX3, NOX4 | TMPRSS2 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.