SCHEMBL25821374

SCHEMBL25821374

N#C[C@@]1(c2ccc3c(N)ncnn23)O[C@@](CO)(C(F)F)[C@@H](O)[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20834799 0.85 TMPRSS2 (0.39) TMPRSS2
SCHEMBL25821376 0.84 ACVRL1 (0.36) —
SCHEMBL22372336 0.83 TMPRSS2 (0.40) TMPRSS2
SCHEMBL22393486 0.83 TMPRSS2 (0.40) TMPRSS2
SCHEMBL20834797 0.83 TMPRSS2 (0.40) TMPRSS2
SCHEMBL20834794 0.83 TMPRSS2 (0.38) TMPRSS2
SCHEMBL22393459 0.82 TMPRSS2 (0.39) TMPRSS2
SCHEMBL23054722 0.81 TMPRSS2 (0.38) TMPRSS2
SCHEMBL20819183 0.81 TMPRSS2 (0.38) TMPRSS2
SCHEMBL20819272 0.80 TMPRSS2 (0.39) TMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2023-07-13 — — US disclosed
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG PNP, TYMP, PIGS TMPRSS2 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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