Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 18/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139746 | 0.86 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL1247032 | 0.85 | SLC6A2 (0.42) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27189669 | 0.85 | SLC6A2 (0.39) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL29542823 | 0.84 | POLB (0.44) | SLC6A2SLC6A3SLC6A4CYP1A2 | |
| SCHEMBL18463247 | 0.82 | TSHR (0.47) | SMN1; SMN2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL996189 | 0.81 | USP2 (0.49) | SMN1; SMN2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL12334940 | 0.81 | SLC6A2 (0.39) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL21635214 | 0.80 | SLC6A2 (0.39) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL21635213 | 0.80 | SLC6A2 (0.39) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL1247006 | 0.79 | USP2 (0.48) | SMN1; SMN2SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795147-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11795147-B2 | Modulators of complex I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-20210061761-A1 | MODULATORS OF COMPLEX I | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061761-A1 | MODULATORS OF COMPLEX I | NDUFAB1, NDUFV1, NDUFB7 | SMN1; SMN2 2091/4885SLC6A2 3156/4885SLC6A3 3824/4885 |
| US-11795147-B2 | Modulators of complex I | NDUFAB1, NDUFV1, NDUFB7 | SMN1; SMN2 2091/4885SLC6A2 3156/4885SLC6A3 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.