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SCHEMBL23057533

SCHEMBL23057533

OC1CN(c2ccc(OC3CC3)cn2)C1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 16/20 0.49
▸ GPR119 Q8TDV5 1/20 0.43
▸ PDE10A Q9Y233 1/20 0.38
▸ TRPV1 Q8NER1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000617 0.81 ACACB (0.48) ACACBGPR119
SCHEMBL30932113 0.81 ACACB (0.48) ACACBGPR119
SCHEMBL23057532 0.80 ACACB (0.49) ACACBGPR119
SCHEMBL23044953 0.78 GPR119 (0.47) ACACBGPR119
SCHEMBL30932097 0.77 ACACB (0.43) ACACBPDE10A
SCHEMBL751184 0.75 GRIN2D (0.47) PDE10A
SCHEMBL15700600 0.75 TRPV1 (0.40) ACACBTRPV1
SCHEMBL19041966 0.72 CLK2 (0.46) ACACBGPR119
SCHEMBL13547453 0.71 PDE10A (0.50) ACACBPDE10A
SCHEMBL22129422 0.71 PDE10A (0.50) GPR119PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409333-B Phenylpyrrolidine compounds 武汉人福创新药物研发中心有限公司 2024-06-14 — — CN disclosed
WO-2021036953-A1 PHENYLPYRROLIDINE COMPOUND 湖北生物医药产业技术研究院有限公司 2021-03-04 — — WO disclosed
WO-2021036953-A1 PHENYLPYRROLIDINE COMPOUND 湖北生物医药产业技术研究院有限公司 2021-03-04 — — WO disclosed
CN-112409333-A Phenylpyrrolidines 湖北生物医药产业技术研究院有限公司 2021-02-26 — — CN disclosed
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