Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932113 | 0.97 | ACACB (0.48) | ACACBGPR119MAPTUBE2TALDH1A1 | |
| SCHEMBL19041966 | 0.86 | CLK2 (0.46) | ACACBGPR119HRH3 | |
| SCHEMBL23057533 | 0.81 | ACACB (0.49) | ACACBGPR119 | |
| SCHEMBL14650779 | 0.77 | UBE2T (0.51) | MAPTUBE2TALDH1A1LMNAALOX12 | |
| SCHEMBL27837554 | 0.76 | UBE2T (0.50) | MAPTUBE2TALDH1A1LMNAALOX12 | |
| SCHEMBL23057532 | 0.74 | ACACB (0.49) | ACACBGPR119 | |
| SCHEMBL28566122 | 0.74 | ACACB (0.45) | ACACBGPR119HRH3 | |
| SCHEMBL22666788 | 0.73 | CHRM4 (0.50) | ACACBGPR119HRH3RET | |
| SCHEMBL12240393 | 0.72 | CHRNA7 (0.50) | MAPTUBE2TALDH1A1LMNAALOX12 | |
| SCHEMBL23044953 | 0.72 | GPR119 (0.47) | ACACBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997024-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-28 | — | — | EP | disclosed |