Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227963 | 0.81 | ACACB (0.39) | ACACB | |
| SCHEMBL23057533 | 0.78 | ACACB (0.49) | GPR119ACACB | |
| SCHEMBL22129474 | 0.78 | PDE10A (0.46) | GPR119 | |
| SCHEMBL23057532 | 0.77 | ACACB (0.49) | GPR119ACACB | |
| SCHEMBL20000617 | 0.72 | ACACB (0.48) | GPR119ACACB | |
| SCHEMBL30932113 | 0.72 | ACACB (0.48) | GPR119ACACB | |
| SCHEMBL6576692 | 0.68 | KDM4E (0.55) | GPR119 | |
| SCHEMBL28910792 | 0.68 | KCNH2 (0.42) | GPR119ACACB | |
| SCHEMBL22129464 | 0.67 | SMO (0.41) | — | |
| SCHEMBL25365054 | 0.66 | GPR119 (0.46) | GPR119ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |