SCHEMBL23058286

SCHEMBL23058286

c1ccc(-c2nc(-c3ccc4ccccc4c3)nc(-c3cccc4oc5ccc(-c6cccc7oc8cc(-n9c%10ccccc%10c%10ccccc%109)ccc8c67)cc5c34)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTGER4 P35408 1/20 0.32
MET P08581 1/20 0.31
PRKDC P78527 1/20 0.30
MAPT P10636 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23058310 0.95 MET (0.34) ALDH1A1KDM4EMEN1TP53CYP1A2
SCHEMBL23058531 0.95 PTGER4 (0.34) ALDH1A1KDM4EPTGER4BACE1
SCHEMBL23058281 0.94 PTGER4 (0.33) KDM4EPTGER4BACE1
SCHEMBL22916638 0.94 ALDH1A1 (0.35) ALDH1A1KDM4EMEN1TP53CYP1A2
SCHEMBL23058600 0.94 PTGER4 (0.33) KDM4ETP53PTGER4BACE1
SCHEMBL23058560 0.94 PTGER4 (0.33) PTGER4BACE1
SCHEMBL23058055 0.94 PTGER4 (0.35) PTGER4PRKDCBACE1
SCHEMBL24363571 0.93 ALDH1A1 (0.33) ALDH1A1KDM4EMEN1TP53CYP1A2
SCHEMBL23058356 0.93 PLA2G2A (0.34) PTGER4PRKDCBACE1
SCHEMBL24363427 0.93 ALDH1A1 (0.35) ALDH1A1KDM4EMEN1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021037401-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-03-04 WO disclosed