Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180879 | 0.86 | CTSK (0.47) | CTSKCTSS | |
| SCHEMBL24178454 | 0.82 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL9911449 | 0.79 | CA1 (0.52) | CTSKCTSSSYKCA1CA2 | |
| SCHEMBL1722314 | 0.78 | CTSS (0.57) | CTSKCTSSSYKCA1CA2 | |
| SCHEMBL5115667 | 0.78 | CTSS (0.57) | CTSKCTSSSYKCA1CA2 | |
| SCHEMBL15627225 | 0.78 | CTSK (0.46) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL21309491 | 0.76 | CTSK (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL20757550 | 0.76 | CTSK (0.49) | CTSKCTSSSYKCA1CA2 | |
| SCHEMBL22109892 | 0.74 | CTSK (0.50) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL102361 | 0.74 | CTSK (0.47) | CTSKCTSSSYKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021041539-A2 | COMPOUNDS AND METHODS OF USE | Ferro Therapeutics, Inc. (US) | 2021-03-04 | — | — | WO | disclosed |