SCHEMBL30180879

SCHEMBL30180879

CCCC[C@@H](CC#C[Si](C)(C)C)NC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 17/20 0.47
▸ CTSS P25774 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23059044 0.86 CTSK (0.43) CTSKCTSS
SCHEMBL8357414 0.81 CTSK (0.61) CTSKCTSS
SCHEMBL21292943 0.80 PLA2G2C (0.38) CTSKCTSS
SCHEMBL21292940 0.80 PLA2G2C (0.38) CTSKCTSS
SCHEMBL28012265 0.78 CTSK (0.56) CTSKCTSS
SCHEMBL25735228 0.78 CTSK (0.56) CTSKCTSS
SCHEMBL16705144 0.78 CTSK (0.56) CTSKCTSS
SCHEMBL23515315 0.78 CTSK (0.56) CTSKCTSS
SCHEMBL18644348 0.78 CTSK (0.56) CTSKCTSS
SCHEMBL14279380 0.78 CTSK (0.56) CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3759075-B1 COMPOUNDS WITH FERROPTOSIS INDUCING ACTIVITY AND METHODS OF THEIR USE FERRO THERAPEUTICS INC (US) 2025-07-23 — — EP disclosed
US-20230039846-A1 COMPOUNDS AND METHODS OF USE FERRO THERAPEUTICS INC (US) 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039846-A1 COMPOUNDS AND METHODS OF USE AIFM2, GPX4, GPX1 CTSK 820/4885CTSS 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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