SCHEMBL23059638

SCHEMBL23059638

CCCC(OC(=O)CCCN(C)I)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.40
MAPT P10636 2/20 0.35
MAPK1 P28482 1/20 0.35
DNM1 Q05193 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PRKCA P17252 1/20 0.31
PRKCE Q02156 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCD Q05655 1/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26415084 0.88 LMNA (0.39) LMNAMAPTMAPK1DNM1ALDH1A1
SCHEMBL4757907 0.80 LMNA (0.44) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL17882020 0.78 ALDH1A1 (0.44) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL17860698 0.77 LMNA (0.39) LMNAMAPTMAPK1ALDH1A1TDP1
SCHEMBL17878555 0.75 LMNA (0.40) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL24593948 0.75 LMNA (0.53) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL23059643 0.74 LMNA (0.38) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL29131231 0.72 LMNA (0.65) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL28676563 0.72 LMNA (0.65) LMNAMAPTMAPK1ALDH1A1PRKCA
SCHEMBL29577585 0.72 LMNA (0.65) LMNAMAPTMAPK1ALDH1A1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210061979-A1 POLYMER, RESIN COMPOSITION, MOLDED ARTICLE, AND PRODUCTION METHOD FOR POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-04 US disclosed