Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003755 | 0.88 | SRD5A2 (0.55) | SRD5A2RARBRARGMEN1CYP1A2 | |
| Aminobenzoic Acid SCHEMBL28344387 | 0.83 | TSHR (0.52) | SRD5A2RARBRARGMEN1CYP1A2 | |
| Aminobenzoic Acid SCHEMBL11323913 | 0.83 | TSHR (0.63) | SRD5A2CYP1A2TP53TSHRRXRA | |
| Aminobenzoic Acid SCHEMBL5874326 | 0.83 | TSHR (0.63) | SRD5A2CYP1A2TP53TSHRRXRA | |
| Terephthalic Acid SCHEMBL7648718 | 0.82 | TSHR (0.71) | SRD5A2MEN1KMT2ATP53TSHR | |
| Terephthalic Acid SCHEMBL9717815 | 0.82 | TSHR (0.71) | SRD5A2MEN1KMT2ATP53TSHR | |
| Aminobenzoic Acid SCHEMBL8249 | 0.82 | TSHR (0.71) | SRD5A2MEN1KMT2ATP53TSHR | |
| Aminobenzoic Acid SCHEMBL1768920 | 0.82 | TSHR (0.71) | SRD5A2MEN1KMT2ATP53TSHR | |
| Bisphenol A SCHEMBL1683933 | 0.82 | ESR1 (0.55) | SRD5A2RARBRARGMEN1CYP1A2 | |
| Aminobenzoic Acid SCHEMBL28176703 | 0.81 | TSHR (0.60) | SRD5A2CYP1A2TP53TSHRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | POLN, POLB, POLRMT | SRD5A2 3901/4885RARB 1842/4885RARG 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.