Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.38 |
| ▸ | SOD1 | P00441 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24123891 | 0.86 | SCN9A (0.41) | SCN9ATACR1SOD1RXRARXRB | |
| SCHEMBL13144932 | 0.83 | RXRA (0.45) | SCN9ATACR1SOD1RXRARXRB | |
| SCHEMBL22546656 | 0.83 | MAPT (0.46) | SCN9ATACR1SOD1RXRARXRB | |
| SCHEMBL10199723 | 0.81 | ALDH1A1 (0.40) | SCN9ATACR1SOD1RXRARXRB | |
| SCHEMBL21916107 | 0.80 | SCN9A (0.40) | SCN9ASOD1RXRARXRBRXRG | |
| SCHEMBL22546658 | 0.78 | MEN1 (0.35) | SCN9ATACR1HTT | |
| SCHEMBL10084735 | 0.78 | RXRA (0.40) | TACR1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL21610851 | 0.77 | FFAR1 (0.41) | REN | |
| SCHEMBL2797059 | 0.77 | ALDH1A1 (0.50) | SCN9ASOD1ALDH1A1 | |
| SCHEMBL21916354 | 0.77 | CETP (0.35) | TACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941912-B1 | PESTICIDALLY ACTIVE AZOLE AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| EP-3867237-B1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20230143596-A1 | PESTICIDALLY ACTIVE DIAZINE-BISAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20230143596-A1 | PESTICIDALLY ACTIVE DIAZINE-BISAMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-11 | — | — | US | disclosed |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-02 | — | — | US | disclosed |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| US-20210395217-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-23 | — | — | US | disclosed |
| WO-2021037614-A1 | PESTICIDALLY ACTIVE PYRAZINE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143596-A1 | PESTICIDALLY ACTIVE DIAZINE-BISAMIDE COMPOUNDS | DDT, ACHE, NIT2 | SCN9A 164/4885TACR1 2209/4885SOD1 340/4885 |
| US-20210395217-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | DDT, ACHE, CYP51A1 | SCN9A 260/4885TACR1 1079/4885SOD1 708/4885 |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | SCN9A 206/4885TACR1 1159/4885SOD1 645/4885 |
| US-20220169629-A1 | PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | SCN9A 240/4885TACR1 1715/4885SOD1 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.