SCHEMBL230634

SCHEMBL230634

CC(=O)OC(=O)/C=C\C(=O)OC(C)=O

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
TSHR P16473 2/20 0.67
HCAR2 Q8TDS4 6/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
TDP1 Q9NUW8 3/20 0.45
HSD17B10 Q99714 2/20 0.45
ATM Q13315 1/20 0.35
LMNA P02545 3/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825979 1.00 ALDH1A1 (0.67) ALDH1A1TSHRHCAR2KEAP1NFE2L2
SCHEMBL14152614 1.00 ALDH1A1 (0.67) ALDH1A1TSHRHCAR2KEAP1NFE2L2
Acetic Acid SCHEMBL29018083 0.94 ALDH1A1 (0.59) ALDH1A1TSHRHCAR2KEAP1NFE2L2
SCHEMBL9474617 0.89 HCAR2 (0.56) ALDH1A1TSHRHCAR2KEAP1NFE2L2
SCHEMBL8760880 0.89 HCAR2 (0.56) ALDH1A1TSHRHCAR2KEAP1NFE2L2
SCHEMBL8760886 0.89 HCAR2 (0.56) ALDH1A1TSHRHCAR2KEAP1NFE2L2
SCHEMBL11044892 0.87 HCAR2 (0.54) ALDH1A1TSHRHCAR2KEAP1NFE2L2
SCHEMBL1695596 0.85
SCHEMBL779039 0.85
SCHEMBL28977028 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2558 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117050746-A Multifunctional monodisperse homogeneous fluorescent microsphere, fluorescent microsphere with core-shell structure, preparation method and application 北京化工大学 2023-11-14 CN claimed
US-20230312606-A1 MCL-1 INHIBITOR FORMULATIONS AMGEN INC. (US) 2023-10-05 US claimed
EP-4203922-A1 MCL-1 INHIBITOR FORMULATIONS Amgen Inc. (US) 2023-07-05 EP claimed
WO-2023095183-A1 A PHARMACEUTICAL COMPOSITION AND A SOLID DOSAGE FORM THEREOF JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (JO) 2023-06-01 WO claimed
US-20230135608-A1 PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE AS AN ACTIVE INGREDIENT PROVIDES A SPECIFIC PHARMACOKINETIC PARAMETER CURACLE CO., LTD. (KR) 2023-05-04 US claimed
US-20230058942-A1 EXTENDED RELEASE MULTIPARTICULATES OF RANOLAZINE SUN PHARMACEUTICAL IND LTD (IN) 2023-02-23 US claimed
WO-2023007514-A1 IMPROVED ORAL BIOAVAILABLE PHARMACEUTICAL COMPOSITIONS DR. REDDY'S LABORATORIES LIMITED (IN) 2023-02-02 WO claimed
EP-2813218-B1 METHOD FOR PRODUCING AQUEOUS ENTERIC COATING LIQUID, SOLID PREPARATION, AND METHOD FOR PRODUCING SAME SHINETSU CHEMICAL CO (JP) 2022-08-24 EP claimed
WO-2022049604-A1 PROCESS FOR PREPARING REVEFENACIN AND INTERMEDIATES THEROF CIPLA LIMITED (IN) 2022-03-10 WO claimed
CN-113647993-A Noninvasive intestinal component collection capsule and using method thereof 成都医学院 2021-11-16 CN claimed
US-4661162-A MIXTURE OF POLYMER WITH POLYANIONIC POLYMER WHICH IS SOLUBLE AT LOW PH SANKYO COMPANY, LIMITED (JP) 1987-04-28 US claimed
EP-0144201-A2 Plate cleaner for electrophotolithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1985-06-12 EP claimed
EP-0135983-A2 Low molucular weight hair spray resin GAF CORPORATION (US) 1985-04-03 EP claimed
US-4497847-A MONO AND DIESTERS OF GLYCEROL AND SATURATED CARBOXYLIC ACIDS AS PLASTICIZERS SANKYO COMPANY, LIMITED (JP) 1985-02-05 US claimed
EP-0122815-A1 Enteric-soluble preparations and a process for their production SANKYO COMPANY LIMITED (JP) 1984-10-24 EP claimed
EP-0108504-A1 A process for coating solid pharmaceutical preparations and coated preparations thus obtained SANKYO COMPANY LIMITED (JP) 1984-05-16 EP claimed
EP-0010938-B1 PROCESS AND COMPOSITIONS FOR PREPARING IMPACT-RESISTANT POLYAMIDE RESINS, AND ARTICLES MADE FROM SUCH RESINS MONSANTO COMPANY (US) 1983-03-16 EP claimed
US-4320213-A High-impact polyamide molding resin compositions MONSANTO COMPANY (US) 1982-03-16 US claimed
EP-0010938-A1 Process and compositions for preparing impact-resistant polyamide resins, and articles made from such resins MONSANTO COMPANY (US) 1980-05-14 EP claimed
US-4039333-A Photographic materials having improved anti-halation layers FUJI PHOTO FILM CO., LTD. (JA) 1977-08-02 US claimed