SCHEMBL8760880

SCHEMBL8760880

CC(=O)OC(=O)/C=C\C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.56
ALDH1A1 P00352 5/20 0.53
TSHR P16473 4/20 0.53
TP53 P04637 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
EGLN3 Q9H6Z9 1/20 0.47
TDP1 Q9NUW8 3/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
HSD17B10 Q99714 3/20 0.41
ALOX15 P16050 2/20 0.41
RECQL P46063 2/20 0.41
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760886 1.00 HCAR2 (0.56) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL9474617 1.00 HCAR2 (0.56) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL11044892 0.97 HCAR2 (0.54) HCAR2ALDH1A1TSHRTP53EGLN1
Acetic Acid SCHEMBL29018083 0.89 ALDH1A1 (0.59) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL230634 0.89 ALDH1A1 (0.67) HCAR2ALDH1A1TSHRTDP1KDM4E
SCHEMBL825979 0.89 ALDH1A1 (0.67) HCAR2ALDH1A1TSHRTDP1KDM4E
SCHEMBL14152614 0.89 ALDH1A1 (0.67) HCAR2ALDH1A1TSHRTDP1KDM4E
Fumaric Acid SCHEMBL8605709 0.89 ALDH1A1 (0.67) HCAR2ALDH1A1TSHRTP53EGLN1
Maleic Acid SCHEMBL27671940 0.89 ALDH1A1 (0.67) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL4949804 0.83 HCAR2 (0.60) HCAR2ALDH1A1TSHRTP53EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113647993-B Noninvasive intestinal component collection capsule and application method thereof 成都医学院 2023-06-16 CN claimed
CN-110437122-A A kind of rubber anti-recovery agent 1,3- bismaleimide n-propane and its synthetic method SHANDONG YANGGU HUATAI CHEMICAL CO LTD 2019-11-12 CN claimed
US-20190047246-A1 HOT-MELT LAMINATED DECORATIVE LAMINATE PROFOL KUNSTSTOFFE GMBH (DE) 2019-02-14 US claimed
CN-109070529-A Heat laminate decor laminate 普洛夫尔塑料有限公司 2018-12-21 CN claimed
CN-109021064-A A kind of preparation method of enalapril maleate 扬子江药业集团有限公司 2018-12-18 CN claimed
CN-108047658-A A kind of Biodegradable polyester agricultural mulching 新疆康润洁环保科技股份有限公司 2018-05-18 CN claimed
EP-0037622-A2 Drug delivery insert for controlled ocular therapy ALZA CORPORATION (US) 1981-10-14 EP claimed
US-4281654-A Drug delivery system for controlled ocular therapy ALZA CORPORATION (US) 1981-08-04 US claimed
JP-56065823-A None JP disclosed
CN-117881475-A Amine functionalized fibers for direct air capture 克莱姆沃克斯有限公司 2024-04-12 CN disclosed
CN-113354605-B Separation device and process for maleic anhydride hydrogenation product 常茂生物化学工程股份有限公司 2023-07-21 CN disclosed
CN-113647993-B Noninvasive intestinal component collection capsule and application method thereof 成都医学院 2023-06-16 CN disclosed
CN-111465736-B Gelled composite material and preparation method thereof 皮层复合材料公司 2023-04-11 CN disclosed
CN-111777621-B Novel application of quinazoline derivative tyrosine kinase inhibitor 山东轩竹医药科技有限公司 2023-03-10 CN disclosed
EP-0494145-A1 IMPACT RESISTANT POLYAMIDE COMPOSITION. ALLIED SIGNAL AUTOMOTIVE OF CA (US) 1992-07-15 EP disclosed
EP-0440923-A1 Polyolefin resinsompositions and process for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-14 EP disclosed
EP-0440922-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-14 EP disclosed
EP-0164778-A1 Detergent powder compositions containing sodium perborate monohydrate UNILEVER N.V. (NL) 1985-12-18 EP disclosed
JP-S5665823-A N-ETHYLCARBAMINOMETHYLISOLEUCINE PHARMACEUTICAL FOR ORAL ADMINISTRATION AJINOMOTO CO INC 1981-06-03 JP disclosed
US-3955027-A FLUOROCARBON POLYMERS, EXTENDERS THE DOW CHEMICAL COMPANY (US) 1976-05-04 US disclosed