Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 8/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434970 | 0.90 | ALDH1A1 (1.00) | ALDH1A1ALOX12SMN1; SMN2HPGDKCNH2 | |
| SCHEMBL12069271 | 0.89 | ALDH1A1 (0.81) | ALDH1A1ALOX12SMN1; SMN2HPGDKCNH2 | |
| SCHEMBL21357791 | 0.87 | ALDH1A1 (0.83) | ALDH1A1ALOX12SMN1; SMN2HPGDKCNH2 | |
| SCHEMBL14859923 | 0.86 | ALDH1A1 (0.81) | ALDH1A1ALOX12SMN1; SMN2HPGDKCNH2 | |
| SCHEMBL12069268 | 0.86 | ALDH1A1 (0.81) | ALDH1A1ALOX12SMN1; SMN2HPGDKCNH2 | |
| SCHEMBL14946919 | 0.82 | ALDH1A1 (0.69) | ALDH1A1ALOX12SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL15328470 | 0.82 | ALDH1A1 (0.78) | ALDH1A1ALOX12SMN1; SMN2KCNH2CYP1A2 | |
| SCHEMBL23068164 | 0.81 | ALDH1A1 (0.83) | ALDH1A1ALOX12SMN1; SMN2KCNH2CYP1A2 | |
| SCHEMBL14859224 | 0.81 | ALDH1A1 (0.77) | ALDH1A1ALOX12SMN1; SMN2HPGDKCNH2 | |
| SCHEMBL13439903 | 0.81 | RAB9A (0.74) | SMN1; SMN2MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814366-B2 | Antiviral compounds and use thereof | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2023-11-14 | — | — | US | disclosed |
| EP-3765454-B1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | UNIV DEGLI STUDI DI SIENA (IT) | 2023-11-08 | — | — | EP | disclosed |
| US-20210070737-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | UNIVERSITA DEGLE STUDI DI SIENA (IT) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814366-B2 | Antiviral compounds and use thereof | MAVS, EIF2AK2, SARS1 | ALDH1A1 2154/4885ALOX12 2331/4885SMN1; SMN2 2276/4885 |
| US-20210070737-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, EIF2AK2, SARS1 | ALDH1A1 2154/4885ALOX12 2331/4885SMN1; SMN2 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.