Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 2/20 | 0.35 |
| ▸ | GALR1 | P47211 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872989 | 0.84 | BUB1 (0.40) | PDE1BCCNE1CDK2PDGFRAAXL | |
| SCHEMBL23069175 | 0.78 | CNR1 (0.43) | PDE1BCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL29873478 | 0.78 | CNR1 (0.43) | PDE1BCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL29872519 | 0.78 | PDE1B (0.34) | PDE1BPDGFRACNR2 | |
| SCHEMBL29872865 | 0.77 | PDE1B (0.50) | PDE1BCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL29872986 | 0.77 | CNR2 (0.45) | PDE1BCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL23069164 | 0.77 | PDE1B (0.50) | PDE1BCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL29872618 | 0.75 | CNR1 (0.39) | PDE1BCNR2CNR1ALDH1A1LMNA | |
| SCHEMBL29873199 | 0.73 | CACNA1B (0.39) | CDK2CNR2CNR1ALDH1A1KMT2A | |
| SCHEMBL29873129 | 0.70 | MAPT (0.46) | CNR2CNR1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306640-A1 | HYDANTOIN DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306640-A1 | HYDANTOIN DERIVATIVE | DDR1, DDR2, DDRGK1 | PDE1B 1600/4885CCNE1 161/4885CDK2 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.