⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23071909 | 1.00 | — | — | |
| SCHEMBL23071864 | 0.92 | — | — | |
| SCHEMBL23071865 | 0.92 | — | — | |
| SCHEMBL23071799 | 0.85 | NMT2 (0.45) | — | |
| SCHEMBL28941746 | 0.84 | LMNA (0.36) | — | |
| SCHEMBL23433027 | 0.84 | PGA5 (0.37) | — | |
| Hydrochloric Acid SCHEMBL18825009 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL18825006 | 0.83 | — | — | |
| SCHEMBL23071956 | 0.81 | — | — | |
| SCHEMBL23071817 | 0.81 | USP2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163458-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI SA (FR) | 2021-06-03 | — | — | US | disclosed |
| US-10941139-B2 | Cryptophycin compounds and conjugates, their preparation and their therapeutic use | SANOFI (FR) | 2021-03-09 | — | — | US | disclosed |