Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29903006 | 0.86 | MAPK1 (0.51) | MAPK1POLBRAB9AALDH1A1HPGD | |
| SCHEMBL20339581 | 0.86 | MAPK1 (0.51) | MAPK1POLBRAB9AALDH1A1HPGD | |
| SCHEMBL4365650 | 0.76 | PTPN1 (0.49) | RAB9AKEAP1ALDH1A1MAPTHDAC1 | |
| SCHEMBL20339548 | 0.75 | KDM4E (0.51) | MAPK1POLBRAB9AALDH1A1LMNA | |
| SCHEMBL29902945 | 0.75 | KDM4E (0.51) | MAPK1POLBRAB9AALDH1A1LMNA | |
| SCHEMBL21794443 | 0.71 | ALDH1A1 (0.50) | POLBALDH1A1LMNAMAPTHPGD | |
| SCHEMBL23073616 | 0.71 | KDM4E (0.64) | KEAP1ALDH1A1LMNAMAPTHDAC1 | |
| SCHEMBL5261897 | 0.70 | JAK2 (0.46) | RAB9AKEAP1ALDH1A1MAPTHPGD | |
| SCHEMBL11649083 | 0.70 | NPC1 (0.55) | RAB9AALDH1A1MAPTHPGDHTT | |
| SCHEMBL7541890 | 0.69 | KEAP1 (0.55) | RAB9AKEAP1ALDH1A1MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562822-B1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | MITOBRIDGE INC (US) | 2021-03-10 | — | — | EP | disclosed |