SCHEMBL23074293

SCHEMBL23074293

c1ccc2c3c(ccc2c1)OCNC3

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
MAPT P10636 1/20 0.49
OXTR P30559 1/20 0.47
HSD17B10 Q99714 2/20 0.44
CYP1A2 P05177 1/20 0.44
GLA P06280 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
SIRT1 Q96EB6 1/20 0.44
LMNA P02545 1/20 0.42
VDR P11473 1/20 0.40
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
HPRT1 P00492 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27844872 0.86 OXTR (0.44) KDM4EMAPTOXTRHSD17B10CYP1A2
SCHEMBL22743887 0.83 KDM4E (0.46) KDM4EMAPTHSD17B10CYP1A2GLA
SCHEMBL5038910 0.74 HSD17B10 (0.46) KDM4EMAPTHSD17B10CYP1A2GLA
SCHEMBL7473565 0.72 KDM4E (0.56) KDM4EMAPTHSD17B10CYP1A2GLA
SCHEMBL30830197 0.72 KDM4E (0.56) KDM4EMAPTHSD17B10CYP1A2GLA
SCHEMBL23074296 0.71 OXTR (0.47) KDM4EOXTRHSD17B10LMNAGAA
SCHEMBL31712961 0.71 KDM4E (0.44) KDM4EMAPTHSD17B10CYP1A2GLA
SCHEMBL31712929 0.71 KDM4E (0.41) KDM4EMAPTHSD17B10CYP1A2GLA
SCHEMBL9327518 0.70 HSD17B10 (0.41) KDM4EMAPTHSD17B10CYP1A2GLA
Water SCHEMBL16634424 0.70 KDM4E (0.54) KDM4EMAPTHSD17B10CYP1A2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210147680-A1 RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER, AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-05-20 US disclosed
EP-3790039-A1 RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER, AND SEMICONDUCTOR DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-03-10 EP disclosed
CN-102336779-A Dihydronaphtho or dihydroanthra-1,3-oxazine derivatives and synthesis method thereof UNIV SHANGHAI 2012-02-01 CN disclosed
CN-102336779-A Dihydronaphtho or dihydroanthra-1,3-oxazine derivatives and synthesis method thereof UNIV SHANGHAI 2012-02-01 CN disclosed