Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | MMP3 | P08254 | 4/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | MMP8 | P22894 | 4/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | FCER2 | P06734 | 2/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039559 | 0.81 | MMP1 (0.56) | MMP1FOLH1MMP2MMP3NPY1R | |
| SCHEMBL11491134 | 0.80 | OPRD1 (0.78) | OPRM1OPRD1 | |
| SCHEMBL25139715 | 0.79 | MMP1 (0.57) | MMP1FOLH1MMP2MMP3MMP9 | |
| SCHEMBL24084078 | 0.79 | OPRM1 (0.52) | MMP1OPRM1OPRD1MMP2MMP3 | |
| SCHEMBL30656942 | 0.79 | IL1RN (0.55) | MMP1OPRM1OPRD1MMP2MMP3 | |
| SCHEMBL25627199 | 0.78 | OPRD1 (0.46) | MMP1OPRM1OPRD1MMP2NPY1R | |
| SCHEMBL7400674 | 0.78 | PSMB5 (0.69) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL22517714 | 0.78 | CAPN1 (0.60) | MMP1FOLH1MMP2MMP3MMP9 | |
| SCHEMBL31256940 | 0.78 | OPRD1 (0.69) | OPRM1OPRD1NPY1RNPY2RNPY4R | |
| SCHEMBL25139854 | 0.78 | GRIA1 (0.59) | MMP1MMP2MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046426-A9 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2021046426-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2021-03-11 | — | — | WO | disclosed |