SCHEMBL23079540

SCHEMBL23079540

CCOC(=O)c1ccsc1-c1cccs1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
KDM4E B2RXH2 5/20 0.52
GAA P10253 3/20 0.52
MAPT P10636 3/20 0.52
KEAP1 Q14145 1/20 0.52
KMT2A Q03164 3/20 0.51
HPGD P15428 3/20 0.50
TSHR P16473 2/20 0.50
CASP1 P29466 1/20 0.50
TP53 P04637 1/20 0.48
POLB P06746 1/20 0.48
NPSR1 Q6W5P4 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30625687 0.83 KMT2A (0.50) ALDH1A1KDM4EGAAMAPTKMT2A
SCHEMBL3609310 0.81 TSHR (0.58) ALDH1A1KDM4EGAAMAPTHPGD
SCHEMBL20042499 0.81 TSHR (0.45) ALDH1A1KDM4EGAAMAPTKMT2A
SCHEMBL11957029 0.80 ALDH1A1 (0.60) ALDH1A1KDM4EGAAMAPTKEAP1
SCHEMBL12028370 0.80 ALDH1A1 (0.41) ALDH1A1KDM4EGAAMAPTKEAP1
SCHEMBL12028371 0.79 ALDH1A1 (0.40) ALDH1A1KDM4EGAAMAPTKEAP1
SCHEMBL29403462 0.79 GABRA1 (0.43) ALDH1A1KDM4EGAAMAPTKEAP1
SCHEMBL12123475 0.79 ALDH1A1 (0.59) ALDH1A1KDM4EGAAMAPTKEAP1
SCHEMBL29824592 0.78 PRSS1 (0.55) ALDH1A1KDM4EGAAMAPTKEAP1
SCHEMBL15357812 0.77 MAPT (0.42) ALDH1A1KDM4EGAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957282-A Near-infrared absorption organic small-molecule photovoltaic material based on benzothiophene/fluorine substituted benzothiophene derivative 东华理工大学 2022-08-30 CN disclosed
US-20210071004-A1 NEAR-INFRARED ABSORBING DYE, OPTICAL FILTER, AND IMAGING DEVICE AGC Inc. (JP) 2021-03-11 US disclosed