SCHEMBL20042499

SCHEMBL20042499

CCOC(=O)c1ccsc1-c1cc2sc(-c3sccc3C(=O)OCC)cc2s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 8/20 0.44
MAPT P10636 5/20 0.44
HSD17B10 Q99714 5/20 0.44
RAB9A P51151 4/20 0.44
HPGD P15428 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
GAA P10253 3/20 0.44
NPC1 O15118 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALOX15 P16050 2/20 0.44
LMNA P02545 2/20 0.44
PKM P14618 2/20 0.43
NFKB1 P19838 1/20 0.43
STAT1 P42224 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
MAPK1 P28482 1/20 0.42
POLB P06746 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15357812 0.90 MAPT (0.42) TSHRALDH1A1MAPTHSD17B10RAB9A
SCHEMBL1498209 0.83 KMT2A (0.44) ALDH1A1MAPTHSD17B10RAB9AHPGD
SCHEMBL23079540 0.81 ALDH1A1 (0.52) TSHRALDH1A1MAPTHSD17B10RAB9A
SCHEMBL24530055 0.80 KMT2A (0.40) TSHRALDH1A1MAPTHSD17B10RAB9A
SCHEMBL6126655 0.78 KMT2A (0.40) ALDH1A1MAPTHSD17B10RAB9AHPGD
SCHEMBL14636130 0.77 POLB (0.45) TSHRALDH1A1MAPTHSD17B10RAB9A
SCHEMBL3609310 0.77 TSHR (0.58) TSHRALDH1A1MAPTHSD17B10RAB9A
SCHEMBL20235829 0.77 GPR35 (0.45) ALDH1A1MAPTHSD17B10RAB9AHPGD
SCHEMBL6126273 0.76 PTPN2 (0.43) ALDH1A1MAPTHSD17B10HPGDGAA
SCHEMBL15594582 0.75 ALDH1A1 (0.53) TSHRALDH1A1MAPTHSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839155-B2 Organic semiconducting compounds RAYNERGY TEK INC. (TW) 2023-12-05 US disclosed
US-11839155-B2 Organic semiconducting compounds RAYNERGY TEK INC. (TW) 2023-12-05 US disclosed
EP-3523308-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2023-09-06 EP disclosed
US-11196005-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2021-12-07 US disclosed
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 US disclosed
US-10991893-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2021-04-27 US disclosed
US-20210070770-A1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2021-03-11 US disclosed
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
US-20200052216-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
US-20190237672-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2019-08-01 US disclosed
WO-2018065350-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed
WO-2018065352-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed
WO-2018065356-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839155-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC TSHR 4717/4885ALDH1A1 2672/4885MAPT 32/4885
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS OCIAD2, OCIAD1, OSTC TSHR 4717/4885ALDH1A1 2672/4885MAPT 32/4885
US-20210070770-A1 ORGANIC SEMICONDUCTING COMPOUNDS OCIAD2, OCIAD1, OSTC TSHR 4717/4885ALDH1A1 2672/4885MAPT 32/4885
US-10991893-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC TSHR 4717/4885ALDH1A1 2672/4885MAPT 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.