Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.55 |
| ▸ | LCK | P06239 | 12/20 | 0.55 |
| ▸ | JAK3 | P52333 | 18/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18884637 | 0.90 | BTK (0.64) | BTKLCKJAK3EGFR | |
| SCHEMBL18884550 | 0.89 | JAK3 (0.62) | BTKLCKJAK3 | |
| SCHEMBL21947866 | 0.89 | BTK (0.55) | BTKLCKJAK3EGFR | |
| SCHEMBL23081194 | 0.88 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL21855202 | 0.84 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL21946319 | 0.84 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL18296155 | 0.84 | LCK (0.73) | BTKLCKJAK3EGFR | |
| SCHEMBL25605387 | 0.84 | BTK (0.59) | BTKLCKJAK3EGFR | |
| SCHEMBL18884392 | 0.83 | JAK3 (0.69) | BTKLCKJAK3EGFR | |
| SCHEMBL25605382 | 0.83 | BTK (0.62) | BTKLCKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070748-A1 | INHIBITORS OF BRUTONS TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210070748-A1 | INHIBITORS OF BRUTONS TYROSINE KINASE | BTK, LYN, LCK | BTK 1/4885LCK 3/4885JAK3 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.