Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046825 | 0.98 | SIGMAR1 (0.43) | EPHX1SIGMAR1TSHRALDH1A1LMNA | |
| SCHEMBL4747287 | 0.95 | SIGMAR1 (0.44) | EPHX1SIGMAR1TSHRALDH1A1LMNA | |
| SCHEMBL841070 | 0.95 | SIGMAR1 (0.44) | EPHX1SIGMAR1TSHRALDH1A1LMNA | |
| SCHEMBL11699658 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL9212478 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL27800763 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL9204346 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL24353239 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL9541689 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL14625028 | 0.91 | EPHX1 (0.48) | EPHX1TSHRALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210299107-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2021-09-30 | — | — | US | disclosed |
| US-20210069358-A1 | COMPOSITIONS AND METHODS TO DETECT GLUA1 IN BRAIN AND TO IDENTIFY THE PRESENCE OF GLUA1-MEDIATED POST-TRAUMATIC STRESS DISORDER AND OTHER NEUROLOGICAL DISORDERS | NEUROVATION LABS INC (US) | 2021-03-11 | — | — | US | disclosed |
| CN-107406534-A | Ionomer resin, ionomer solution containing the ionomer resin, laminate, member, electrochemical element, and electrochemical device | 日东电工株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-107405617-A | Anion exchange membrane, electrochemical element and electrochemical device having the same | 日东电工株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-104167564-B | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-105074514-A | Polarizing plate | SUMITOMO CHEMICAL CO | 2015-11-18 | — | — | CN | disclosed |
| CN-102300719-B | Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method for producing relief printing plate | FUJIFILM CORP | 2013-09-04 | — | — | CN | disclosed |
| CN-103135347-A | Resin composition for laser engraving, flexographic printing plate precursor for laser engraving and process for producing same, and flexographic printing plate and process for making same | FUJIFILM CORP | 2013-06-05 | — | — | CN | disclosed |
| CN-102967995-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing same, process for making relief printing plate, and relief printing plate | FUJIFILM CORP | 2013-03-13 | — | — | CN | disclosed |
| CN-102621812-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving, and relief printing plate and process for making the same | FUJIFILM CORP | 2012-08-01 | — | — | CN | disclosed |
| CN-102540713-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing same, and process for making relief printing plate | FUJIFILM CORP | 2012-07-04 | — | — | CN | disclosed |
| CN-102540712-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing the same, and relief printing plate and process for making the same | FUJIFILM CORP | 2012-07-04 | — | — | CN | disclosed |
| CN-102436139-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing the same, relief printing plate and process for making the same | FUJIFILM CORP | 2012-05-02 | — | — | CN | disclosed |
| CN-102300719-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving, relief printing plate and method for producing relief printing plate | — | 2011-12-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210069358-A1 | COMPOSITIONS AND METHODS TO DETECT GLUA1 IN BRAIN AND TO IDENTIFY THE PRESENCE OF GLUA1-MEDIATED POST-TRAUMATIC STRESS DISORDER AND OTHER NEUROLOGICAL DISORDERS | GRIA1, GRIA2, GRIA3 | EPHX1 1422/4885SIGMAR1 1912/4885TSHR 4138/4885 |
| US-20210299107-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS | AIFM2, GPX1, SLC7A11 | EPHX1 1664/4885SIGMAR1 3804/4885TSHR 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.