Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841070 | 1.00 | SIGMAR1 (0.44) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL23082604 | 0.95 | EPHX1 (0.42) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL26046825 | 0.93 | SIGMAR1 (0.43) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL11491450 | 0.90 | LMNA (0.42) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21799677 | 0.89 | DNM1 (0.41) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21799765 | 0.89 | DNM1 (0.41) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21799463 | 0.89 | DNM1 (0.41) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21800094 | 0.89 | DNM1 (0.41) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21800100 | 0.89 | DNM1 (0.41) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21799697 | 0.89 | DNM1 (0.41) | SIGMAR1LMNACNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130721-A1 | PREPARATION OF SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |