SCHEMBL2308296

SCHEMBL2308296

NS(=O)(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.79

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.79
CA1 P00915 9/20 0.79
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
HTR6 P50406 3/20 0.70
CA12 O43570 2/20 0.69
CA9 Q16790 2/20 0.69
IL1RN P18510 1/20 0.66
KEAP1 Q14145 1/20 0.66
ERAP1 Q9NZ08 1/20 0.66
ALDH1A1 P00352 1/20 0.61
PKM P14618 1/20 0.61
MAPT P10636 1/20 0.61
POLB P06746 1/20 0.60
GAA P10253 1/20 0.59
HPGD P15428 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2235290 0.92 CA1 (0.73) CA2CA1MEN1KMT2AHTR6
Phenyl(Phenylsulfonyl)Amine SCHEMBL11825113 0.87 CA1 (0.89) CA2CA1MEN1KMT2AHTR6
SCHEMBL2237044 0.87 CA2 (0.75) CA2CA1MEN1KMT2ACA12
SCHEMBL9001184 0.87 KEAP1 (0.79) MEN1KMT2AHTR6IL1RNKEAP1
SCHEMBL2235397 0.83 CA1 (0.69) CA2CA1MEN1KMT2ACA12
SCHEMBL2723618 0.82 HTR6 (1.00) CA2CA1MEN1KMT2AHTR6
SCHEMBL2235306 0.82 CA1 (0.63) CA2CA1MEN1KMT2AHTR6
SCHEMBL27466837 0.81 CA1 (1.00) CA2CA1MEN1KMT2ACA12
SCHEMBL31681389 0.81 CA2 (0.66) CA2CA1MEN1KMT2AHTR6
Hydrochloric Acid SCHEMBL18953392 0.81 HTR6 (0.97) CA2CA1MEN1KMT2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210356879-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE, AND PLANOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2021-11-18 US disclosed
EP-2349990-A1 ARYL-PHENYL-SULFONAMIDE-PHENYLENE COMPOUNDS AND THEIR USE Pimco 2664 Limited (GB) 2011-08-03 EP disclosed