Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 1.00 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.82 |
| ▸ | CNR2 | P34972 | 6/20 | 0.73 |
| ▸ | CNR1 | P21554 | 3/20 | 0.73 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.73 |
| ▸ | MLNR | O43193 | 1/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | PDE9A | O76083 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | LDHA | P00338 | 1/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20658132 | 1.00 | OPRM1 (1.00) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL20658115 | 1.00 | OPRM1 (1.00) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL30018283 | 1.00 | OPRM1 (1.00) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL25341241 | 0.99 | OPRM1 (0.98) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL13214117 | 0.94 | OPRM1 (0.88) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL24449664 | 0.94 | OPRM1 (0.88) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL25985040 | 0.94 | OPRM1 (0.88) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL18909010 | 0.94 | OPRM1 (0.88) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL29351701 | 0.94 | OPRM1 (0.88) | OPRM1ACE2CNR2CNR1TRPV1 | |
| SCHEMBL25878176 | 0.94 | OPRM1 (0.88) | OPRM1ACE2CNR2CNR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911401-B2 | Tryptamine compositions for enhancing neurite outgrowth | TURTLE BEAR HOLDINGS, LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-11911401-B2 | Tryptamine compositions for enhancing neurite outgrowth | TURTLE BEAR HOLDINGS, LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-11660305-B2 | Tryptamine compositions for enhancing neurite outgrowth | TURTLE BEAR HOLDINGS, LLC (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210251976-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | TURTLE BEAR HOLDINGS LLC (US) | 2021-08-19 | — | — | US | disclosed |
| US-20210069170-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | TURTLE BEAR HOLDINGS, LLC | 2021-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660305-B2 | Tryptamine compositions for enhancing neurite outgrowth | HTR1B, HTR6, BDNF | OPRM1 88/4885ACE2 4051/4885CNR2 24/4885 |
| US-20210251976-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | HTR1B, HTR6, BDNF | OPRM1 88/4885ACE2 4051/4885CNR2 24/4885 |
| US-20210069170-A1 | TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH | HTR1B, HTR6, BDNF | OPRM1 88/4885ACE2 4051/4885CNR2 24/4885 |
| US-11911401-B2 | Tryptamine compositions for enhancing neurite outgrowth | HTR1B, HTR6, BDNF | OPRM1 88/4885ACE2 4051/4885CNR2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.