SCHEMBL2308324

SCHEMBL2308324

C=CC(=O)OCCC[Si](C)(C)N[Si](C)(C)CCCOC(=O)C=C

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 1/20 0.56
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HCAR2 Q8TDS4 3/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ACHE P22303 4/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28472770 0.85 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9313444 0.83 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL308812 0.83 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26187833 0.83 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1681567 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9064667 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3628945 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2310559 0.81 ATM (0.44) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL17138332 0.80 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9808738 0.80 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2865720-B1 Photocurable coating composition, laminate, and automotive headlamp covering sheet SHINETSU CHEMICAL CO (JP) 2017-05-03 EP claimed
EP-2868717-B1 Titania-containing coating composition and coated article SHINETSU CHEMICAL CO (JP) 2017-04-19 EP claimed
EP-2868717-A1 Titania-containing coating composition and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-06 EP claimed
EP-2865720-A1 Photocurable coating composition, laminate, and automotive headlamp covering sheet Shin-Etsu Chemical Co., Ltd. (JP) 2015-04-29 EP claimed
EP-3756892-B1 INKJET HEAD AND METHOD FOR PRODUCING SAME KONICA MINOLTA INC (JP) 2023-08-23 EP disclosed
US-20210016572-A1 INKJET HEAD AND METHOD FOR PRODUCING SAME Konica Minolta, Inc. (JP) 2021-01-21 US disclosed
CN-104610877-B The product of coating composition and coating containing titanium oxide 信越化学工业株式会社 2019-04-23 CN disclosed
EP-2865720-B1 Photocurable coating composition, laminate, and automotive headlamp covering sheet SHINETSU CHEMICAL CO (JP) 2017-05-03 EP disclosed
EP-2868717-B1 Titania-containing coating composition and coated article SHINETSU CHEMICAL CO (JP) 2017-04-19 EP disclosed
US-20150125707-A1 TITANIA-CONTAINING COATING COMPOSITION AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-07 US disclosed
EP-2868717-A1 Titania-containing coating composition and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2015-05-06 EP disclosed
US-20150118483-A1 PHOTOCURABLE COATING COMPOSITION, LAMINATE, AND AUTOMOTIVE HEADLAMP COVERING SHEET SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-04-30 US disclosed
EP-2865720-A1 Photocurable coating composition, laminate, and automotive headlamp covering sheet Shin-Etsu Chemical Co., Ltd. (JP) 2015-04-29 EP disclosed
EP-2028184-B1 Method of producing organosilylamine containing radiation-polymerizable functional group and organosilylamine containing radiation-polymerizable functional group SHINETSU CHEMICAL CO (JP) 2011-08-03 EP disclosed
US-7863473-B2 Method of producing organosilylamine containing radiation-polymerizable functional group and organosilylamine containing radiation-polymerizable functional group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-01-04 US disclosed
US-20090054673-A1 METHOD OF PRODUCING ORGANOSILYLAMINE CONTAINING RADIATION-POLYMERIZABLE FUNCTIONAL GROUP AND ORGANOSILYLAMINE CONTAINING RADIATION-POLYMERIZABLE FUNCTIONAL GROUP SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-02-26 US disclosed
EP-2028184-A1 Method of producing organosilylamine containing radiation-polymerizable functional group and organosilylamine containing radiation-polymerizable functional group Shin-Etsu Chemical Co., Ltd. (JP) 2009-02-25 EP disclosed
US-6307081-B1 MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. DOW CORNING SILICONE COMPANY, LTD. (JP) 2001-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054673-A1 METHOD OF PRODUCING ORGANOSILYLAMINE CONTAINING RADIATION-POLYMERIZABLE FUNCTIONAL GROUP AND ORGANOSILYLAMINE CONTAINING RADIATION-POLYMERIZABLE FUNCTIONAL GROUP STOM, SI, AS3MT TSHR 2580/4885ALDH1A1 805/4885CYP3A4 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.