Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.60 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 5/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180003 | 0.85 | DYRK1A (0.58) | DYRK1AFSCN1CASP3SENP7SENP8 | |
| SCHEMBL1761323 | 0.83 | DGAT1 (0.52) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| SCHEMBL2306840 | 0.83 | DYRK1A (0.48) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| Bicarbonate SCHEMBL2310949 | 0.82 | CASP3 (0.58) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| SCHEMBL1762122 | 0.81 | DGAT1 (0.79) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| SCHEMBL1748234 | 0.81 | DGAT1 (0.58) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| Bicarbonate SCHEMBL2315409 | 0.81 | CASP3 (0.54) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| SCHEMBL1748235 | 0.81 | DGAT1 (0.58) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| Bicarbonate SCHEMBL2311087 | 0.81 | CASP3 (0.54) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 | |
| SCHEMBL2309828 | 0.81 | DGAT1 (0.51) | DYRK1AFSCN1DGAT1CSGALNACT1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633722-B1 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2011-08-03 | — | — | EP | claimed |