SCHEMBL23085486

SCHEMBL23085486

O=C(NCCOCCN(CCOCCNC(=O)OCc1ccccc1)Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.76
LMNA P02545 1/20 0.76
HTT P42858 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPT P10636 1/20 0.52
TGM2 P21980 1/20 0.48
KEAP1 Q14145 2/20 0.47
NFE2L2 Q16236 2/20 0.47
ACHE P22303 3/20 0.46
SLC1A3 P43003 1/20 0.45
SLC1A1 P43005 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KAT2B Q92831 1/20 0.43
GAA P10253 1/20 0.43
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11990340 0.88 SMN1; SMN2 (0.73) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL7372302 0.87 SMN1; SMN2 (1.00) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL13531477 0.86 SMN1; SMN2 (0.71) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL23871966 0.86 LMNA (0.61) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL30823376 0.86 SMN1; SMN2 (0.97) SMN1; SMN2LMNAHTTL3MBTL1MAPT
Hydrochloric Acid SCHEMBL30495884 0.85 LMNA (0.60) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL26840796 0.83 SMN1; SMN2 (0.85) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL23662928 0.83 SMN1; SMN2 (0.66) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL29486860 0.82 SMN1; SMN2 (0.83) SMN1; SMN2LMNAHTTL3MBTL1MAPT
SCHEMBL25566258 0.82 SMN1; SMN2 (0.83) SMN1; SMN2LMNAHTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20210228727-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2021-07-29 US disclosed
US-20210220478-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2021-07-22 US disclosed
WO-2021046549-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2021-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A SMN1; SMN2 4221/4885LMNA 3451/4885HTT 4145/4885
US-20210228727-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A SMN1; SMN2 4221/4885LMNA 3451/4885HTT 4145/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A SMN1; SMN2 4221/4885LMNA 3451/4885HTT 4145/4885
US-20210220478-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A SMN1; SMN2 4221/4885LMNA 3451/4885HTT 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.