Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19392610 | 0.82 | SERPINE1 (0.58) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL420439 | 0.82 | SERPINE1 (0.58) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL418773 | 0.79 | SERPINE1 (0.77) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL417528 | 0.79 | SERPINE1 (0.57) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL418515 | 0.76 | SERPINE1 (0.54) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL422315 | 0.76 | SERPINE1 (0.81) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL29838729 | 0.76 | SERPINE1 (0.81) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL16022191 | 0.74 | HDAC8 (0.76) | HDAC8HDAC6DEGS1HDAC3HDAC11 | |
| SCHEMBL418422 | 0.74 | SERPINE1 (0.52) | SERPINE1HDAC8HDAC6DEGS1HDAC3 | |
| SCHEMBL27851426 | 0.74 | SERPINE1 (0.60) | SERPINE1HDAC8HDAC6DEGS1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607348-B1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE INC (JP) | 2021-03-17 | — | — | EP | disclosed |