Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086149 | 0.82 | SERPINE1 (0.56) | SERPINE1MAPTHDAC8HDAC6DEGS1 | |
| SCHEMBL12388857 | 0.81 | TAS1R3 (0.71) | RAB9AMAPTSMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL16022191 | 0.81 | HDAC8 (0.76) | RAB9AMAPTSMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27851426 | 0.78 | SERPINE1 (0.60) | SERPINE1MAPTHDAC8HDAC6DEGS1 | |
| SCHEMBL5260499 | 0.78 | LMNA (0.57) | RAB9AMAPTSMN1; SMN2NPC1MEN1 | |
| SCHEMBL16705207 | 0.77 | HDAC8 (0.71) | RAB9AMAPTSMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL422315 | 0.77 | SERPINE1 (0.81) | SERPINE1MAPTHDAC8HDAC6DEGS1 | |
| SCHEMBL29838729 | 0.77 | SERPINE1 (0.81) | SERPINE1MAPTHDAC8HDAC6DEGS1 | |
| SCHEMBL15214829 | 0.77 | HDAC8 (0.71) | RAB9AMAPTSMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL4449040 | 0.76 | TAS1R3 (0.69) | RAB9AMAPTSMN1; SMN2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258356-B1 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | CT INGENIERIA GENETICA BIOTECNOLOGIA (CU) | 2017-09-27 | — | — | EP | disclosed |