Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417135 | 0.87 | SERPINE1 (0.66) | SERPINE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL420345 | 0.81 | SERPINE1 (0.69) | SERPINE1NPC1RAB9AHTTMEN1 | |
| SCHEMBL418849 | 0.81 | SERPINE1 (0.67) | SERPINE1NPC1RAB9AHTTMEN1 | |
| SCHEMBL418848 | 0.80 | SERPINE1 (0.79) | SERPINE1NPC1RAB9AHTTMEN1 | |
| SCHEMBL417156 | 0.79 | SERPINE1 (0.61) | SERPINE1NPC1RAB9AHTTMEN1 | |
| SCHEMBL6710125 | 0.75 | SERPINE1 (0.48) | SERPINE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6713754 | 0.74 | SERPINE1 (0.43) | SERPINE1L3MBTL1 | |
| SCHEMBL1307945 | 0.74 | GPR35 (0.58) | SERPINE1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6713933 | 0.73 | RXFP1 (0.41) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL19554341 | 0.73 | HDAC3 (0.45) | SERPINE1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607348-B1 | Plasminogen Activator Inhibitor-1 Inhibitor | RENASCIENCE INC (JP) | 2021-03-17 | — | — | EP | claimed |