Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554168 | 0.87 | KCNMA1 (0.43) | HDAC3TAS1R3TAS1R1TAS1R2KCNMA1 | |
| SCHEMBL19554150 | 0.80 | KCNK2 (0.52) | HDAC3SERPINE1 | |
| SCHEMBL1307013 | 0.75 | KCNMA1 (0.56) | SERPINE1KCNMA1RAB9ASMN1; SMN2 | |
| SCHEMBL5474886 | 0.74 | GRIK1 (0.44) | RAB9ASMN1; SMN2 | |
| SCHEMBL19575630 | 0.74 | HDAC3 (0.46) | HDAC3SERPINE1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6713933 | 0.74 | RXFP1 (0.41) | KCNMA1KCNQ3KCNQ2NPC1ALDH1A1 | |
| SCHEMBL1308878 | 0.74 | GPR35 (0.55) | SERPINE1KCNMA1KCNQ3KCNQ2NPC1 | |
| SCHEMBL19554352 | 0.74 | GPR35 (0.45) | HDAC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6708921 | 0.73 | ALOX15 (0.51) | ALOX15 | |
| SCHEMBL23086154 | 0.73 | SERPINE1 (0.52) | SERPINE1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |