Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.41 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.40 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713754 | 0.95 | SERPINE1 (0.43) | SERPINE1KDM4ENPSR1RXFP1NHERF1 | |
| SCHEMBL6713211 | 0.91 | PARP14 (0.42) | SERPINE1KDM4ENPSR1RXFP1MEN1 | |
| SCHEMBL6710319 | 0.91 | CHRNB2 (0.43) | SERPINE1MAPTNHERF1PLCG2F10 | |
| SCHEMBL6708019 | 0.90 | GPR35 (0.44) | MAPTNHERF1STK33PLCG2 | |
| SCHEMBL6711906 | 0.89 | NHERF1 (0.46) | NPC1RAB9ALMNASMN1; SMN2NHERF1 | |
| SCHEMBL6713933 | 0.89 | RXFP1 (0.41) | KDM4ERXFP1MEN1KMT2ANPC1 | |
| SCHEMBL6708001 | 0.88 | MEN1 (0.45) | RXFP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL6710112 | 0.88 | MAP3K5 (0.45) | KDM4ERXFP1NPC1MAPTRAB9A | |
| SCHEMBL6708855 | 0.88 | KDR (0.45) | KDM4ENPSR1MEN1KMT2AMAPT | |
| SCHEMBL6707952 | 0.87 | PRSS12 (0.39) | SERPINE1RXFP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SERPINE1 2108/4885KDM4E 1582/4885NPSR1 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.