Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295270 | 0.74 | CYP3A4 (0.57) | MAPTNOS1CYP3A4LMNAALOX15 | |
| SCHEMBL3302468 | 0.70 | NOS1 (0.56) | MAPTNOS1CYP3A4LMNAALOX15 | |
| SCHEMBL3887990 | 0.70 | CYP3A4 (0.57) | MAPTNOS1CYP3A4LMNAALOX15 | |
| SCHEMBL917562 | 0.70 | HTT (0.42) | NOS1LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL3733557 | 0.69 | TXNRD1 (0.46) | MAPTNOS1CYP3A4LMNAALOX15 | |
| SCHEMBL9126256 | 0.69 | MAPT (0.39) | MAPTNOS1CYP3A4LMNAALOX15 | |
| SCHEMBL12746195 | 0.68 | AURKA (0.37) | NOS1POLBIDO1KDM4E | |
| SCHEMBL8944274 | 0.68 | DYRK1A (0.31) | — | |
| SCHEMBL23092892 | 0.68 | KDM4E (0.38) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL732343 | 0.68 | SMN1; SMN2 (0.47) | MAPTNOS1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050688-A1 | COMPOUNDS AND USES THEREOF | X-CHEM, INC. (US) | 2021-03-18 | — | — | WO | disclosed |