Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25252180 | 0.77 | OPRL1 (0.33) | PDE10AOPRL1HDAC4 | |
| SCHEMBL12523394 | 0.77 | PDE8B (0.36) | PDE10AOPRL1HDAC4 | |
| SCHEMBL485877 | 0.77 | HDAC4 (0.35) | PDE10AOPRL1HDAC4GRM2 | |
| SCHEMBL20582117 | 0.74 | TKT (0.39) | PDE10AOPRL1HDAC4GRM2 | |
| SCHEMBL27973605 | 0.74 | LOXL2 (0.35) | OPRL1 | |
| SCHEMBL20582080 | 0.74 | HDAC4 (0.33) | PDE10AOPRL1HDAC4GRM2 | |
| SCHEMBL18397055 | 0.74 | TDP1 (0.33) | PDE10AOPRL1HDAC4 | |
| SCHEMBL11086191 | 0.73 | MAPK1 (0.39) | PDE10AOPRL1HDAC4 | |
| SCHEMBL22719359 | 0.72 | NOTUM (0.40) | PDE10AGRM2 | |
| SCHEMBL24785081 | 0.72 | PDE10A (0.38) | PDE10AOPRL1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947206-B2 | cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947206-B2 | cGAS antagonist compounds | CGAS, STING1, GLS2 | PDE10A 38/4885OPRL1 155/4885HDAC4 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.