Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13410540 | 0.85 | SLC7A5 (0.57) | SLC6A3 | |
| SCHEMBL16130498 | 0.85 | SLC6A4 (0.47) | TAAR1SLC6A2SLC6A4 | |
| SCHEMBL12142605 | 0.85 | SLC7A5 (0.57) | SLC6A3 | |
| SCHEMBL20751459 | 0.83 | ANPEP (0.37) | TAAR1SLC6A2 | |
| SCHEMBL14679503 | 0.83 | ANPEP (0.37) | TAAR1SLC6A2 | |
| SCHEMBL15080989 | 0.81 | ALDH1A1 (0.45) | — | |
| SCHEMBL16360424 | 0.81 | EPHX2 (0.47) | — | |
| SCHEMBL251733 | 0.79 | ANPEP (0.62) | TAAR1SLC6A2SLC6A3SLC6A4MAOA | |
| SCHEMBL5183224 | 0.79 | ANPEP (0.62) | TAAR1SLC6A2SLC6A3SLC6A4MAOA | |
| SCHEMBL8136474 | 0.79 | TAAR1 (0.59) | TAAR1SLC6A2SLC6A3SLC6A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3336103-B1 | ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE | SUTRO BIOPHARMA INC (US) | 2021-03-17 | — | — | EP | disclosed |