Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.59 |
| ▸ | HRH1 | P35367 | 4/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097759 | 0.88 | MAPT (0.59) | HRH3HRH1KCNH2HRH2DRD2 | |
| SCHEMBL23097681 | 0.88 | DRD2 (0.53) | HRH3HRH1KCNH2HRH2DRD2 | |
| SCHEMBL23097688 | 0.87 | SLC6A2 (0.57) | HRH3HRH1KCNH2HRH2DRD2 | |
| SCHEMBL2020791 | 0.87 | DRD2 (0.64) | HRH3HRH1KCNH2HRH2DRD2 | |
| SCHEMBL23097617 | 0.87 | MAPT (0.59) | HRH3KCNA5KCNH2DRD2MAPT | |
| SCHEMBL23097690 | 0.87 | MAPT (0.65) | KCNH2DRD2MAPTHSD17B10TP53 | |
| SCHEMBL23097610 | 0.87 | KCNH2 (0.69) | HRH3HRH1KCNA5KCNH2HRH2 | |
| SCHEMBL23097600 | 0.87 | HTR1A (0.66) | HRH3HRH1HRH2DRD2MAPT | |
| SCHEMBL23097804 | 0.85 | MAPT (0.61) | HRH3KCNH2DRD2MAPTTSHR | |
| SCHEMBL23097724 | 0.85 | DRD2 (0.57) | HRH3HRH1KCNH2HRH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170334-B1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | UNIV EMORY (US) | 2021-03-17 | — | — | EP | disclosed |