Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097784 | 0.90 | DRD2 (0.61) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097661 | 0.88 | DRD3 (0.65) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097788 | 0.88 | DRD2 (0.66) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097599 | 0.87 | DRD2 (0.60) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097749 | 0.86 | DRD2 (0.58) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097605 | 0.86 | DRD2 (0.59) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097671 | 0.86 | DRD2 (0.56) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097704 | 0.86 | KCNH2 (0.59) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097677 | 0.86 | KCNH2 (0.69) | DRD2DRD3DRD4KCNH2SLC6A2 | |
| SCHEMBL23097672 | 0.86 | SLC6A2 (0.69) | DRD2DRD3DRD4KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170334-B1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | UNIV EMORY (US) | 2021-03-17 | — | — | EP | disclosed |