Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.37 |
| ▸ | NOS2 | P35228 | 6/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23098226 | 0.89 | MBOAT4 (0.41) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL21573991 | 0.84 | RORC (0.40) | RORCNOS2IDH1 | |
| SCHEMBL18973007 | 0.81 | CYP3A4 (0.40) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL18972899 | 0.79 | MBOAT4 (0.40) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL21022599 | 0.78 | MBOAT4 (0.39) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL22875356 | 0.78 | MBOAT4 (0.39) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL22875560 | 0.78 | MBOAT4 (0.39) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL20826041 | 0.77 | MBOAT4 (0.53) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL21022880 | 0.77 | MBOAT4 (0.53) | RORCNOS2USP2STAT3NFE2L2 | |
| SCHEMBL21085842 | 0.77 | MBOAT4 (0.53) | RORCNOS2USP2STAT3NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353190-B1 | C4-MODIFIED OLEANOLIC ACID DERIVATIVES FOR INHIBITION OF IL-17 AND OTHER USES | REATA PHARMACEUTICALS INC (US) | 2021-03-17 | — | — | EP | disclosed |