Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681294 | 0.77 | HRH3 (0.35) | HRH3ALDH1A1RAB9A | |
| SCHEMBL21641504 | 0.74 | KDM4E (0.44) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL23099449 | 0.73 | PRMT6 (0.37) | HRH3CYP2A6 | |
| SCHEMBL8845493 | 0.71 | LOXL2 (0.36) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL13876041 | 0.67 | HRH3 (0.42) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL30639263 | 0.66 | KDM4E (0.47) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL8845897 | 0.66 | CHRNA10 (0.36) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL151261 | 0.66 | CHEK1 (0.68) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| Iodide SCHEMBL4213036 | 0.66 | HRH3 (0.41) | CHEK1KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL2384959 | 0.65 | KDM4E (0.80) | CHEK1KDM4ETP53CHRNA10CHRNA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |