Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.33 |
| ▸ | CDC25B | P30305 | 5/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FGF1 | P05230 | 2/20 | 0.32 |
| ▸ | FGF2 | P09038 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309951 | 1.00 | NT5E (0.35) | NT5ELGALS3TYMPPTPN1CDC25B | |
| SCHEMBL2309941 | 0.93 | NT5E (0.39) | NT5ELGALS3TYMPPTPN1CDC25B | |
| SCHEMBL2309944 | 0.93 | NT5E (0.39) | NT5ELGALS3TYMPPTPN1CDC25B | |
| SCHEMBL2314117 | 0.91 | TYMP (0.39) | NT5ELGALS3TYMPSSTR5 | |
| SCHEMBL2311035 | 0.88 | NT5E (0.44) | NT5ELGALS3PTPN1CDC25BPTPN2 | |
| SCHEMBL2311027 | 0.85 | LGALS3 (0.45) | NT5ELGALS3PTPN1CDC25BPTPN2 | |
| SCHEMBL9800967 | 0.82 | SSTR1 (0.42) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL16581497 | 0.81 | SSTR1 (0.43) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL7901248 | 0.81 | SSTR1 (0.43) | NT5EPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL2313402 | 0.81 | TYMP (0.43) | LGALS3TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |