Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | CDC25B | P30305 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312267 | 0.92 | LGALS3 (0.50) | LGALS3SLC6A2TACR2BCHEPTPN1 | |
| SCHEMBL2311035 | 0.89 | NT5E (0.44) | LGALS3BCHEPTPN1CDC25BMAPK1 | |
| SCHEMBL2309951 | 0.85 | NT5E (0.35) | LGALS3BCHEALOX15PTPN1CDC25B | |
| SCHEMBL2309948 | 0.85 | NT5E (0.35) | LGALS3BCHEALOX15PTPN1CDC25B | |
| SCHEMBL9853879 | 0.82 | SLC6A2 (0.47) | SLC6A2TACR2BCHEPTPN1CDC25B | |
| SCHEMBL9853878 | 0.82 | SLC6A2 (0.47) | SLC6A2TACR2BCHEPTPN1CDC25B | |
| SCHEMBL2312270 | 0.80 | NT5E (0.49) | TACR2PTPN1CDC25BMAPK1NT5E | |
| SCHEMBL2314117 | 0.80 | TYMP (0.39) | LGALS3SLC6A2NT5E | |
| SCHEMBL6553208 | 0.80 | LGALS3 (0.46) | LGALS3SLC6A2TACR2BCHEALDH1A1 | |
| SCHEMBL9332545 | 0.79 | LGALS3 (0.52) | LGALS3SLC6A2PTPN1LGALS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |