Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.42 |
| ▸ | CDC25B | P30305 | 8/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312270 | 0.92 | NT5E (0.49) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL2311027 | 0.89 | LGALS3 (0.45) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL2309948 | 0.88 | NT5E (0.35) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL2309951 | 0.88 | NT5E (0.35) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL11102696 | 0.84 | NT5E (0.45) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL16633056 | 0.83 | LGALS3 (0.46) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17456128 | 0.83 | NT5E (0.48) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL8654521 | 0.83 | HTR1A (0.46) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL17456127 | 0.83 | NT5E (0.48) | NT5EPTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL9853892 | 0.82 | PTPN1 (0.52) | NT5EPTPN1CDC25BPTPN2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |