Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099557 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL23099555 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL23099525 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10GABRA2 | |
| SCHEMBL23099456 | 0.84 | AGBL2 (0.34) | GABRA2GABRB2KMT2AMEN1CYP2C9 | |
| SCHEMBL26527673 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10GABRA2 | |
| SCHEMBL23099413 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL21192132 | 0.79 | AKR1B1 (0.36) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL21192133 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL26527683 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL23099539 | 0.79 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |