Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099557 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10JUN | |
| SCHEMBL26527717 | 0.86 | ALKBH1 (0.36) | KDM4EALDH1A1HPGDHSD17B10GABRA2 | |
| SCHEMBL23099596 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10GABRA2 | |
| SCHEMBL23099555 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10JUN | |
| SCHEMBL23099525 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10GABRA2 | |
| SCHEMBL23099413 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10JUN | |
| SCHEMBL26527683 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL23099502 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDGABRA2GABRB2 | |
| SCHEMBL26527689 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL13837930 | 0.75 | ALDH1A1 (0.76) | KDM4EALDH1A1HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089170-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023073090-A1 | IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Janssen Sciences Ireland Unlimited Company (IE) | 2023-05-04 | — | — | WO | disclosed |