SCHEMBL2309971

SCHEMBL2309971

O=c1c2ccccc2sc2cc(CCO)ccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 7/20 0.44
MAPT P10636 7/20 0.44
RAB9A P51151 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
POLB P06746 3/20 0.42
HCRTR1 O43613 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALOX15 P16050 1/20 0.40
GPR3 P46089 1/20 0.39
NFKB1 P19838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2315780 0.92 KDM4E (0.42) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL2307395 0.91 KDM4E (0.55) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL2308278 0.89 KDM4E (0.41) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL9785996 0.84 ALDH1A1 (0.41) KDM4EALDH1A1MAPTRAB9ATDP1
SCHEMBL18243738 0.84 MAPT (0.48) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL18242408 0.82 ALDH1A1 (0.46) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL2315224 0.82 KDM4E (0.42) KDM4EALDH1A1MAPTRAB9AL3MBTL1
SCHEMBL2310251 0.81 MAOA (0.37) KDM4EALDH1A1MAPTRAB9ANPC1
SCHEMBL2313006 0.81 CYP19A1 (0.40) KDM4EALDH1A1MAPTL3MBTL1POLB
SCHEMBL2311180 0.81 KDM4E (0.51) KDM4EALDH1A1MAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101238189-B Conductive adhesives and biomedical articles including same 3M INNOVATIVE PROPERTIES CO 2012-12-05 CN disclosed
US-7989517-B2 Actinic ray curable composition, actinic ray curable ink, and image formation process employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-08-02 US disclosed
CN-101238189-A Conductive adhesives and biomedical articles including same 3M INNOVATIVE PROPERTIES CO (US) 2008-08-06 CN disclosed
US-20070123600-A1 ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, AND IMAGE FORMATION PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-31 US disclosed
CN-1192072-C Conductive adhesive and biomedical electrode 3M INNOVATIVE PROPERTIES CO (US) 2005-03-09 CN disclosed
CN-1413240-A Conductive adhesive and biomedical electrode 3M INNOVATIVE PROPERTIES CO (US) 2003-04-23 CN disclosed