SCHEMBL2315224

SCHEMBL2315224

O=c1c2cc(CCO)ccc2sc2ccc(CCO)cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.42
ALOX5 P09917 1/20 0.42
GAA P10253 1/20 0.42
BACE1 P56817 1/20 0.42
TDP1 Q9NUW8 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA2 P00918 3/20 0.38
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2308278 0.93 KDM4E (0.41) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL2307395 0.92 KDM4E (0.55) KDM4EALDH1A1MAPTGAATDP1
SCHEMBL2315780 0.85 KDM4E (0.42) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL2307733 0.82 MAOA (0.40) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL2307290 0.82 CYP19A1 (0.40) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL2309971 0.82 KDM4E (0.47) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL18903328 0.80 GPR3 (0.50) KDM4EALDH1A1MAPTALOX5GAA
SCHEMBL14436298 0.78 KDM4E (0.48) KDM4EALDH1A1MAPTGAATDP1
SCHEMBL14607511 0.77 KDM4E (0.58) KDM4EALDH1A1MAPTGAATDP1
SCHEMBL7044064 0.77 NPC1 (0.45) KDM4EALDH1A1MAPTTDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989517-B2 Actinic ray curable composition, actinic ray curable ink, and image formation process employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-08-02 US disclosed
US-20070123600-A1 ACTINIC RAY CURABLE COMPOSITION, ACTINIC RAY CURABLE INK, AND IMAGE FORMATION PROCESS EMPLOYING THE SAME KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-31 US disclosed